Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 4/20 | 0.43 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.35 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.35 |
| ▸ | GRM5 | P41594 | 11/20 | 0.35 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.35 |
| ▸ | LPL | P06858 | 1/20 | 0.33 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | TDO2 | P48775 | 1/20 | 0.33 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15796518 | 0.90 | BACE1 (0.41) | BACE1PRMT5WDR77GRM5ROCK1 | |
| SCHEMBL29896800 | 0.90 | BACE1 (0.41) | BACE1PRMT5WDR77GRM5ROCK1 | |
| SCHEMBL2043461 | 0.83 | MEN1 (0.43) | BACE1GRM5 | |
| SCHEMBL30015969 | 0.83 | MEN1 (0.43) | BACE1GRM5 | |
| SCHEMBL15795865 | 0.80 | PRF1 (0.41) | BACE1PRMT5WDR77GRM5ROCK1 | |
| SCHEMBL28988087 | 0.79 | NOTUM (0.43) | BACE1ROCK1LPLLIPGIDO1 | |
| SCHEMBL18766183 | 0.77 | ROCK1 (0.40) | BACE1PRMT5WDR77ROCK1LPL | |
| SCHEMBL18765849 | 0.77 | ROCK1 (0.40) | BACE1PRMT5WDR77ROCK1LPL | |
| SCHEMBL18766181 | 0.77 | ROCK1 (0.40) | BACE1PRMT5WDR77ROCK1LPL | |
| SCHEMBL1226405 | 0.76 | PBRM1 (0.45) | BACE1PRMT5WDR77ROCK1LPL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3426260-A1 | C-GLYCOSIDE COMPOUNDS USEFUL FOR TREATING DISEASE | Fimbrion Therapeutics, Inc. (US) | 2019-01-16 | — | — | EP | disclosed |
| WO-2017156508-A1 | C-GLYCOSIDE COMPOUNDS USEFUL FOR TREATING DISEASE | FIMBRION THERAPEUTICS, INC. (US) | 2017-09-14 | — | — | WO | disclosed |
| WO-2017156508-A1 | C-GLYCOSIDE COMPOUNDS USEFUL FOR TREATING DISEASE | FIMBRION THERAPEUTICS, INC. (US) | 2017-09-14 | — | — | WO | disclosed |