Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17119256 | 1.00 | BACE1 (0.84) | BACE1BACE2 | |
| SCHEMBL17119092 | 1.00 | BACE1 (0.84) | BACE1BACE2 | |
| SCHEMBL17119078 | 0.91 | BACE1 (1.00) | BACE1 | |
| SCHEMBL19333008 | 0.91 | BACE1 (0.77) | BACE1BACE2 | |
| SCHEMBL17119075 | 0.91 | BACE1 (0.77) | BACE1BACE2 | |
| SCHEMBL19333006 | 0.88 | BACE1 (0.67) | BACE1BACE2 | |
| SCHEMBL17119125 | 0.88 | BACE1 (0.67) | BACE1BACE2 | |
| SCHEMBL11917948 | 0.88 | BACE1 (0.79) | BACE1BACE2 | |
| SCHEMBL17815403 | 0.88 | BACE1 (0.79) | BACE1BACE2 | |
| SCHEMBL11918006 | 0.86 | BACE1 (0.84) | BACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9758513-B2 | Dihydrooxazine or oxazepine derivatives having BACE1 inhibitory activity | SHIONOGI & CO., LTD. (JP) | 2017-09-12 | — | — | US | disclosed |