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Sugi Predict / Compounds / SCHEMBL19333201

SCHEMBL19333201

SCHEMBL19333201

[2H]C([2H])(OP(=O)(O)OP(=O)(O)OP(=O)(O)O)[C@@]1(F)O[C@@H](N2C=CC(=O)NC2=C)[C@](C)(O)[C@@H]1O

nearest known ligand 0.38

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
▸ P2RY2 P41231 1/20 0.38
▸ P2RY4 P51582 1/20 0.38
▸ POLA1 P09884 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17357547 0.91 P2RY2 (0.39) P2RY2P2RY4POLA1
SCHEMBL15837250 0.91 P2RY2 (0.39) P2RY2P2RY4POLA1
SCHEMBL17357548 0.91 P2RY2 (0.39) P2RY2P2RY4POLA1
SCHEMBL16639950 0.85 P2RY2 (0.34) P2RY2P2RY4POLA1
SCHEMBL16639949 0.85 P2RY2 (0.34) P2RY2P2RY4POLA1
SCHEMBL15837334 0.85 P2RY2 (0.34) P2RY2P2RY4POLA1
SCHEMBL16640141 0.85 P2RY2 (0.34) P2RY2P2RY4POLA1
SCHEMBL17357713 0.85 P2RY2 (0.37) P2RY2P2RY4POLA1
SCHEMBL15837292 0.84 P2RY2 (0.35) P2RY2P2RY4POLA1
SCHEMBL16368084 0.84 P2RY2 (0.40) P2RY2P2RY4POLA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9758544-B2 Substituted nucleosides, nucleotides and analogs thereof ALIOS BIOPHARMA, INC. (US) 2017-09-12 — — US disclosed
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