Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTK | P33981 | 1/20 | 0.67 |
| ▸ | PIK3CG | P48736 | 15/20 | 0.61 |
| ▸ | PIK3CD | O00329 | 10/20 | 0.61 |
| ▸ | PIK3CA | P42336 | 7/20 | 0.61 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.54 |
| ▸ | RELA | Q04206 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.50 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.49 |
| ▸ | JAK2 | O60674 | 1/20 | 0.48 |
| ▸ | KIT | P10721 | 1/20 | 0.48 |
| ▸ | FLT3 | P36888 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3091846 | 0.85 | PIK3CG (0.80) | TTKPIK3CGPIK3CDPIK3CAPIK3CB | |
| SCHEMBL2187962 | 0.84 | PIK3CG (0.70) | TTKPIK3CGPIK3CDPIK3CAPIK3CB | |
| SCHEMBL12507255 | 0.82 | TTK (0.75) | TTKPIK3CGPIK3CDPIK3CAPIK3CB | |
| SCHEMBL1933260 | 0.82 | TTK (0.59) | TTKPIK3CGPIK3CDPIK3CAPIK3CB | |
| SCHEMBL1933136 | 0.81 | TTK (0.69) | TTKPIK3CGPIK3CDPIK3CAMAPT | |
| SCHEMBL1934192 | 0.80 | TTK (0.64) | TTKPIK3CGPIK3CDPIK3CAPIK3CB | |
| SCHEMBL1931869 | 0.80 | TTK (1.00) | TTKPIK3CGPIK3CDPIK3CALRRK2 | |
| SCHEMBL1933195 | 0.80 | TTK (0.74) | TTKPIK3CGPIK3CDPIK3CAPIK3CB | |
| SCHEMBL16306665 | 0.80 | TTK (0.63) | TTKPIK3CGPIK3CDPIK3CAPIK3CB | |
| SCHEMBL1932155 | 0.80 | PIK3CG (0.70) | TTKPIK3CGPIK3CDPIK3CALRRK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2507236-A1 | TRIAZOLOPYRIDINE DERIVATIVES | Bayer Intellectual Property GmbH (DE) | 2012-10-10 | — | — | EP | claimed |
| WO-2011064328-A1 | TRIAZOLOPYRIDINE DERIVATIVES | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2011-06-03 | — | — | WO | claimed |