Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | FAAH | O00519 | 2/20 | 0.32 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.32 |
| ▸ | CTSL | P07711 | 1/20 | 0.31 |
| ▸ | CTSB | P07858 | 1/20 | 0.31 |
| ▸ | CTSS | P25774 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | SLC18A2 | Q05940 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8915997 | 0.80 | MAPT (0.36) | MAPTALDH1A1L3MBTL1FAAHTRPV1 | |
| SCHEMBL8912335 | 0.77 | MAPT (0.36) | MAPTALDH1A1L3MBTL1FAAHTRPV1 | |
| SCHEMBL12281761 | 0.77 | MAPT (0.33) | MAPTALDH1A1L3MBTL1FAAHTRPV1 | |
| SCHEMBL19334264 | 0.75 | MAPT (0.33) | MAPTALDH1A1L3MBTL1FAAHTRPV1 | |
| SCHEMBL19364749 | 0.74 | MAPT (0.34) | MAPTALDH1A1L3MBTL1FAAHTRPV1 | |
| SCHEMBL12980577 | 0.74 | MAPT (0.34) | MAPTALDH1A1L3MBTL1FAAHTRPV1 | |
| SCHEMBL755311 | 0.74 | MAPT (0.39) | MAPTALDH1A1L3MBTL1FAAHTRPV1 | |
| SCHEMBL8930220 | 0.74 | MAPT (0.39) | MAPTALDH1A1L3MBTL1FAAHTRPV1 | |
| SCHEMBL8908048 | 0.73 | MAPT (0.33) | MAPTALDH1A1L3MBTL1FAAHTRPV1 | |
| SCHEMBL8917069 | 0.72 | EPHX1 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9758487-B2 | Hepatitis C virus inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 2017-09-12 | — | — | US | disclosed |