SCHEMBL19334902

CCCC[C@@H](C(=O)N[C@@H](CS)C(=O)N[C@H](C)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CS)C(N)=O)N1C(=O)N[C@H](C)C1=O

nearest known ligand 0.56

Predicted protein targets (top 3)

	gene	UniProt	supporting neighbours	confidence
▸	MC4R	P32245	6/20	0.56

▸	GHSR	Q92847	9/20	0.51

▸	GRPR	P30550	3/20	0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL23430205	1.00	MC4R (0.56)	MC4RGHSRGRPR
SCHEMBL20108246	1.00	MC4R (0.56)	MC4RGHSRGRPR
SCHEMBL20108332	0.96	MC4R (0.57)	MC4RGHSR
SCHEMBL20108370	0.96	MC4R (0.57)	MC4RGHSR
SCHEMBL19334877	0.94	MC4R (0.55)	MC4RGHSRGRPR
SCHEMBL19334906	0.94	MC4R (0.55)	MC4RGHSRGRPR
SCHEMBL23430158	0.94	MC4R (0.55)	MC4RGHSRGRPR
SCHEMBL23430195	0.91	MC4R (0.55)	MC4RGHSRGRPR
SCHEMBL23430156	0.91	MC4R (0.53)	MC4RGHSRGRPR
SCHEMBL20108376	0.90	MC4R (0.57)	MC4RGHSRGRPR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
US-9758549-B2	Melanocortin receptor ligands modified with hydantoin	IPSEN PHARMA S.A.S. (FR)	2017-09-12	—	—	US	disclosed