Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTK | P33981 | 19/20 | 0.61 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.33 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19336858 | 0.91 | TTK (0.52) | TTK | |
| SCHEMBL17445623 | 0.89 | TTK (0.62) | TTK | |
| SCHEMBL19336811 | 0.89 | TTK (0.59) | TTKMAPK8MAPK10 | |
| SCHEMBL17445625 | 0.83 | TTK (0.75) | TTK | |
| SCHEMBL19336837 | 0.82 | TTK (0.67) | TTK | |
| SCHEMBL19336831 | 0.79 | TTK (0.65) | TTK | |
| SCHEMBL19336838 | 0.79 | TTK (0.75) | TTK | |
| Bay-1217389 SCHEMBL15555839 | 0.77 | TTK (1.00) | TTK | |
| SCHEMBL17571044 | 0.71 | TTK (0.91) | TTK | |
| SCHEMBL16307170 | 0.71 | TTK (0.88) | TTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2961752-B1 | SUBSTITUTED IMIDAZOPYRIDAZINES | Bayer Pharma AG (DE) | 2017-09-13 | — | — | EP | disclosed |