Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTK | P33981 | 20/20 | 0.80 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19336860 | 0.93 | TTK (0.69) | TTK | |
| SCHEMBL17425421 | 0.92 | TTK (0.78) | TTKCYP3A4 | |
| SCHEMBL17590072 | 0.89 | TTK (0.83) | TTK | |
| SCHEMBL469967 | 0.89 | TTK (1.00) | TTKCYP3A4 | |
| SCHEMBL469976 | 0.87 | TTK (0.84) | TTK | |
| SCHEMBL456217 | 0.86 | TTK (0.69) | TTKCYP3A4 | |
| SCHEMBL12987754 | 0.85 | TTK (0.68) | TTKCYP3A4 | |
| SCHEMBL15556481 | 0.85 | TTK (0.68) | TTK | |
| SCHEMBL16001600 | 0.84 | TTK (1.00) | TTK | |
| SCHEMBL470289 | 0.84 | TTK (0.77) | TTKCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2961752-B1 | SUBSTITUTED IMIDAZOPYRIDAZINES | Bayer Pharma AG (DE) | 2017-09-13 | — | — | EP | disclosed |