Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY1 | P47900 | 8/20 | 0.54 |
| ▸ | P2RY2 | P41231 | 4/20 | 0.54 |
| ▸ | P2RX1 | P51575 | 4/20 | 0.54 |
| ▸ | P2RX3 | P56373 | 4/20 | 0.54 |
| ▸ | P2RX2 | Q9UBL9 | 2/20 | 0.54 |
| ▸ | P2RX4 | Q99571 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | SRC | P12931 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | MACROD2 | A1Z1Q3 | 1/20 | 0.51 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.51 |
| ▸ | MACROD1 | Q9BQ69 | 1/20 | 0.51 |
| ▸ | TRPM2 | O94759 | 1/20 | 0.51 |
| ▸ | PARG | Q86W56 | 1/20 | 0.47 |
| ▸ | P2RY11 | Q96G91 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21864396 | 0.87 | P2RY1 (0.57) | P2RY1P2RY2SRCSMN1; SMN2TRPM2 | |
| SCHEMBL21859358 | 0.80 | P2RY1 (0.58) | P2RY1P2RY2P2RX1P2RX3P2RX2 | |
| SCHEMBL6035368 | 0.77 | P2RX1 (0.62) | P2RY1P2RY2P2RX1P2RX3P2RX2 | |
| SCHEMBL6035384 | 0.77 | P2RX1 (0.62) | P2RY1P2RY2P2RX1P2RX3P2RX2 | |
| SCHEMBL24829433 | 0.76 | POLB (0.73) | P2RY1P2RY2P2RX1P2RX3P2RX2 | |
| SCHEMBL13983913 | 0.76 | POLB (0.73) | P2RY1P2RY2P2RX1P2RX3P2RX2 | |
| SCHEMBL9115023 | 0.76 | ADORA2A (0.56) | SMN1; SMN2 | |
| SCHEMBL29514954 | 0.76 | ADORA2A (0.56) | SMN1; SMN2 | |
| SCHEMBL9115027 | 0.76 | ADORA2A (0.56) | SMN1; SMN2 | |
| SCHEMBL22652873 | 0.76 | P2RY1 (0.91) | P2RY1P2RY2P2RX1P2RX3P2RX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2970351-B1 | RIBONUCLEIC ACIDS WITH 4'-THIO-MODIFIED NUCLEOTIDES AND RELATED METHODS | TRANSLATE BIO INC (US) | 2017-09-13 | — | — | EP | disclosed |