Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AB1 | P08238 | 18/20 | 0.69 |
| ▸ | HSP90AA1 | P07900 | 18/20 | 0.69 |
| ▸ | HSP90B1 | P14625 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10214759 | 0.85 | HSP90AB1 (0.73) | HSP90AB1HSP90AA1HSP90B1 | |
| Hydrochloric Acid SCHEMBL382762 | 0.84 | HSP90AB1 (0.72) | HSP90AB1HSP90AA1HSP90B1 | |
| Hypochlorous Acid SCHEMBL12802787 | 0.83 | HSP90AB1 (0.70) | HSP90AB1HSP90AA1HSP90B1 | |
| SCHEMBL30091906 | 0.82 | HSP90AB1 (1.00) | HSP90AB1HSP90AA1HSP90B1 | |
| SCHEMBL30091904 | 0.82 | HSP90AB1 (1.00) | HSP90AB1HSP90AA1HSP90B1 | |
| SCHEMBL383624 | 0.82 | HSP90AB1 (1.00) | HSP90AB1HSP90AA1HSP90B1 | |
| SCHEMBL382859 | 0.79 | HSP90AA1 (0.66) | HSP90AB1HSP90AA1HSP90B1 | |
| SCHEMBL383810 | 0.78 | HSP90AA1 (0.59) | HSP90AB1HSP90AA1HSP90B1 | |
| SCHEMBL384828 | 0.78 | HSP90AA1 (0.67) | HSP90AB1HSP90AA1HSP90B1 | |
| SCHEMBL383083 | 0.77 | HSP90AA1 (0.60) | HSP90AB1HSP90AA1HSP90B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2073804-B1 | HYDROXY-SUBSTITUTED BENZOIC ACID AMIDE COMPOUNDS FOR USE IN THE TREATMENT OF PAIN | ASTEX THERAPEUTICS LTD (GB) | 2017-09-13 | — | — | EP | disclosed |