Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 19/20 | 0.64 |
| ▸ | S1PR3 | Q99500 | 4/20 | 0.51 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL408040 | 0.82 | S1PR1 (0.61) | S1PR1S1PR3NR1H4 | |
| SCHEMBL19339941 | 0.82 | S1PR1 (0.64) | S1PR1S1PR3NR1H4 | |
| SCHEMBL2417621 | 0.78 | S1PR1 (1.00) | S1PR1S1PR3 | |
| SCHEMBL2803637 | 0.78 | S1PR1 (0.73) | S1PR1S1PR3NR1H4 | |
| SCHEMBL12277830 | 0.78 | S1PR1 (0.86) | S1PR1S1PR3NR1H4 | |
| SCHEMBL2813909 | 0.74 | S1PR1 (1.00) | S1PR1S1PR3 | |
| SCHEMBL14926437 | 0.73 | S1PR1 (0.70) | S1PR1NR1H4 | |
| SCHEMBL2813468 | 0.72 | S1PR1 (0.60) | S1PR1S1PR3NR1H4 | |
| SCHEMBL2810457 | 0.72 | S1PR1 (0.61) | S1PR1S1PR3NR1H4 | |
| SCHEMBL408734 | 0.71 | S1PR1 (0.69) | S1PR1S1PR3NR1H4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2414341-B1 | OXADIAZOLE DERIVATIVES | MERCK SERONO SA (CH) | 2017-09-13 | — | — | EP | disclosed |