Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRCP | P42785 | 8/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.43 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.43 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | HPGDS | O60760 | 3/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | HCRTR1 | O43613 | 3/20 | 0.39 |
| ▸ | HCRTR2 | O43614 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19339868 | 1.00 | PRCP (0.45) | PRCPCYP3A4CYP2C9NR1I2ABCB11 | |
| SCHEMBL2707439 | 0.92 | PRCP (0.51) | PRCPCYP3A4CYP2C9NR1I2ABCB11 | |
| SCHEMBL18463052 | 0.92 | PRCP (0.51) | PRCPCYP3A4CYP2C9NR1I2ABCB11 | |
| SCHEMBL2709067 | 0.92 | PRCP (0.51) | PRCPCYP3A4CYP2C9NR1I2ABCB11 | |
| SCHEMBL18463054 | 0.92 | PRCP (0.51) | PRCPCYP3A4CYP2C9NR1I2ABCB11 | |
| SCHEMBL19339508 | 0.92 | PRCP (0.42) | PRCPCYP3A4CYP2C9NR1I2ABCB11 | |
| SCHEMBL690388 | 0.90 | CYP3A4 (0.52) | PRCPCYP3A4CYP2C9NR1I2ABCB11 | |
| SCHEMBL13148034 | 0.90 | CYP3A4 (0.52) | PRCPCYP3A4CYP2C9NR1I2ABCB11 | |
| SCHEMBL204049 | 0.90 | CYP3A4 (0.52) | PRCPCYP3A4CYP2C9NR1I2ABCB11 | |
| SCHEMBL690389 | 0.90 | CYP3A4 (0.52) | PRCPCYP3A4CYP2C9NR1I2ABCB11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3002281-B1 | ANTIVIRAL COMPOUNDS | GILEAD PHARMASSET LLC (US) | 2017-09-13 | — | — | EP | disclosed |