Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.39 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.38 |
| ▸ | NAMPT | P43490 | 1/20 | 0.38 |
| ▸ | MMP2 | P08253 | 1/20 | 0.38 |
| ▸ | MMP13 | P45452 | 1/20 | 0.38 |
| ▸ | MMP14 | P50281 | 1/20 | 0.38 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.38 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.38 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.38 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.38 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.37 |
| ▸ | TPSD1 | Q9BZJ3 | 1/20 | 0.37 |
| ▸ | TPSG1 | Q9NRR2 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15268805 | 0.88 | USP2 (0.46) | USP2SMN1; SMN2HPGDEPHX2OPRD1 | |
| SCHEMBL5216557 | 0.85 | USP2 (0.44) | USP2SMN1; SMN2HPGDEPHX2OPRD1 | |
| SCHEMBL24442411 | 0.84 | USP2 (0.46) | USP2SMN1; SMN2HPGDEPHX2OPRD1 | |
| SCHEMBL1954007 | 0.84 | USP2 (0.49) | USP2SMN1; SMN2HPGDEPHX2OPRD1 | |
| SCHEMBL1586924 | 0.84 | USP2 (0.49) | USP2SMN1; SMN2HPGDEPHX2OPRD1 | |
| SCHEMBL605572 | 0.84 | USP2 (0.49) | USP2SMN1; SMN2HPGDEPHX2OPRD1 | |
| SCHEMBL21551293 | 0.84 | SMN1; SMN2 (0.43) | USP2SMN1; SMN2HPGDEPHX2OPRD1 | |
| SCHEMBL3187327 | 0.83 | USP2 (0.47) | USP2SMN1; SMN2HPGDEPHX2OPRD1 | |
| SCHEMBL8012970 | 0.83 | USP2 (0.47) | USP2SMN1; SMN2HPGDEPHX2OPRD1 | |
| SCHEMBL15657912 | 0.81 | USP2 (0.46) | USP2SMN1; SMN2HPGDEPHX2OPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017156177-A1 | 3-PHOSPHOGLYCERATE DEHYDROGENASE INHIBITORS AND USES THEREOF | RAZE THERAPEUTICS, INC. (US) | 2017-09-14 | — | — | WO | disclosed |