Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 20/20 | 1.00 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.48 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22476049 | 1.00 | PIK3CD (1.00) | PIK3CDPIK3CBPIK3CA | |
| SCHEMBL29869061 | 1.00 | PIK3CD (1.00) | PIK3CDPIK3CBPIK3CA | |
| SCHEMBL22476055 | 0.90 | PIK3CD (0.81) | PIK3CD | |
| SCHEMBL22476057 | 0.90 | PIK3CD (0.81) | PIK3CD | |
| SCHEMBL19344347 | 0.87 | PIK3CD (0.77) | PIK3CD | |
| SCHEMBL369408 | 0.83 | PIK3CD (1.00) | PIK3CDPIK3CBPIK3CA | |
| SCHEMBL369409 | 0.83 | PIK3CD (1.00) | PIK3CDPIK3CBPIK3CA | |
| SCHEMBL19344367 | 0.81 | PIK3CD (1.00) | PIK3CDPIK3CBPIK3CA | |
| SCHEMBL19344345 | 0.81 | PIK3CD (1.00) | PIK3CDPIK3CBPIK3CA | |
| SCHEMBL29530782 | 0.81 | PIK3CD (1.00) | PIK3CDPIK3CBPIK3CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11446301-B2 | Quinoline analogs as phosphatidylinositol 3-kinase inhibitors | NANJING ZHENGXIANG PHARMACEUTICALS CO., LTD. (CN) | 2022-09-20 | — | — | US | disclosed |
| EP-3400227-B1 | QUINOLINE ANALOGS AS PHOSPHATIDYLINOSITOL 3-KINASE INHIBITORS | HANGZHOU ZHENGXIANG PHARMACEUTICALS CO LTD (CN) | 2021-03-31 | — | — | EP | disclosed |
| EP-3400227-B1 | QUINOLINE ANALOGS AS PHOSPHATIDYLINOSITOL 3-KINASE INHIBITORS | HANGZHOU ZHENGXIANG PHARMACEUTICALS CO LTD (CN) | 2021-03-31 | — | — | EP | disclosed |
| US-20210046075-A1 | QUINOLINE ANALOGS AS PHOSPHATIDYLINOSITOL 3-KINASE INHIBITORS | NANJING ZHENGXIANG PHARMACEUTICALS CO., LTD. (CN) | 2021-02-18 | — | — | US | disclosed |
| US-20210046075-A1 | QUINOLINE ANALOGS AS PHOSPHATIDYLINOSITOL 3-KINASE INHIBITORS | NANJING ZHENGXIANG PHARMACEUTICALS CO., LTD. (CN) | 2021-02-18 | — | — | US | disclosed |
| CN-112250665-A | Quinoline analogs as phosphatidylinositol 3-kinase inhibitors | 杭州征祥医药有限公司 | 2021-01-22 | — | — | CN | disclosed |
| US-10792283-B2 | Quinoline analogs as phosphatidylinositol 3-kinase inhibitors | HANGZHOU ZHENGXIANG PHARMACEUTICALS CO., LTD. (CN) | 2020-10-06 | — | — | US | disclosed |
| US-10792283-B2 | Quinoline analogs as phosphatidylinositol 3-kinase inhibitors | HANGZHOU ZHENGXIANG PHARMACEUTICALS CO., LTD. (CN) | 2020-10-06 | — | — | US | disclosed |
| CN-108290898-B | Quinoline analogs as phosphatidylinositol 3-kinase inhibitors | 杭州征祥医药有限公司 | 2020-09-08 | — | — | CN | disclosed |
| WO-2017155741-A1 | QUINOLINE ANALOGS AS PHOSPHATIDYLINOSITOL 3-KINASE INHIBITORS | ZHEJIANG VIMGREEN PHARMA LTD. (CN) | 2017-09-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10792283-B2 | Quinoline analogs as phosphatidylinositol 3-kinase inhibitors | PIK3CD, PI4KB, PIK3CA | PIK3CD 1/4885PIK3CB 9/4885PIK3CA 3/4885 |
| US-11446301-B2 | Quinoline analogs as phosphatidylinositol 3-kinase inhibitors | PIK3CD, PI4KB, PIK3CA | PIK3CD 1/4885PIK3CB 9/4885PIK3CA 3/4885 |
| US-20210046075-A1 | QUINOLINE ANALOGS AS PHOSPHATIDYLINOSITOL 3-KINASE INHIBITORS | PIK3CD, PI4KB, PIK3CA | PIK3CD 1/4885PIK3CB 9/4885PIK3CA 3/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.