Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC10A1 | Q14973 | 9/20 | 0.35 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.32 |
| ▸ | PGR | P06401 | 1/20 | 0.32 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19346992 | 0.90 | MAPT (0.34) | SLC10A1PGR | |
| SCHEMBL22510932 | 0.86 | SLC10A1 (0.33) | SLC10A1GRM4PGR | |
| SCHEMBL22511208 | 0.86 | GRM4 (0.36) | SLC10A1GRM4PGRLRRK2 | |
| SCHEMBL19332096 | 0.82 | SLC10A1 (0.47) | SLC10A1GRM4LRRK2 | |
| SCHEMBL22545643 | 0.80 | SLC10A1 (0.36) | SLC10A1 | |
| SCHEMBL22545644 | 0.79 | SLC10A1 (0.43) | SLC10A1 | |
| SCHEMBL21427927 | 0.78 | SLC10A1 (0.44) | SLC10A1GRM4LRRK2 | |
| SCHEMBL22511068 | 0.78 | SLC10A1 (0.44) | SLC10A1GRM4LRRK2 | |
| SCHEMBL22511269 | 0.77 | SLC10A1 (0.43) | SLC10A1GRM4LRRK2 | |
| SCHEMBL32682269 | 0.77 | SLC10A1 (0.43) | SLC10A1GRM4LRRK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017156255-A1 | ELIMINATION OF HEPATITIS B VIRUS WITH ANTIVIRAL AGENTS | EMORY UNIVERSITY (US) | 2017-09-14 | — | — | WO | disclosed |