Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PHGDH | O43175 | 20/20 | 0.76 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19347480 | 0.92 | PHGDH (0.73) | PHGDH | |
| SCHEMBL31008857 | 0.92 | PHGDH (0.76) | PHGDH | |
| SCHEMBL19347358 | 0.92 | PHGDH (0.76) | PHGDH | |
| SCHEMBL31008836 | 0.91 | PHGDH (0.74) | PHGDH | |
| SCHEMBL20794594 | 0.91 | PHGDH (0.74) | PHGDH | |
| SCHEMBL20794435 | 0.91 | PHGDH (0.74) | PHGDH | |
| SCHEMBL20794775 | 0.87 | PHGDH (0.69) | PHGDH | |
| SCHEMBL31008846 | 0.87 | PHGDH (0.69) | PHGDH | |
| SCHEMBL20794778 | 0.86 | PHGDH (1.00) | PHGDH | |
| SCHEMBL31008848 | 0.86 | PHGDH (1.00) | PHGDH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017156179-A1 | 3-PHOSPHOGLYCERATE DEHYDROGENASE INHIBITORS AND USES THEREOF | RAZE THERAPEUTICS, INC. (US) | 2017-09-14 | — | — | WO | disclosed |