⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6646557 | 0.48 | — | — | |
| SCHEMBL1451472 | 0.45 | — | — | |
| Hydrochloric Acid SCHEMBL3932836 | 0.40 | — | — | |
| SCHEMBL561897 | 0.34 | — | — | |
| SCHEMBL3729569 | 0.31 | — | — | |
| SCHEMBL120273 | 0.29 | — | — | |
| SCHEMBL9326710 | 0.25 | — | — | |
| SCHEMBL10915456 | 0.25 | — | — | |
| SCHEMBL6559802 | 0.25 | — | — | |
| SCHEMBL278498 | 0.25 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 73 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4352055-A1 | O-LINKED THIADIAZOLYL COMPOUNDS AS DNA POLYMERASE THETA INHIBITORS | Ideaya Biosciences, Inc. (US) | 2024-04-17 | — | — | EP | disclosed |
| EP-4255573-A1 | SUBSTITUTED THIADIAZOLYL DERIVATIVES AS DNA POLYMERASE THETA INHIBITORS | Ideaya Biosciences, Inc. (US) | 2023-10-11 | — | — | EP | disclosed |
| CN-116134036-A | Compounds and methods for modulating splicing | 雷密克斯医疗公司 | 2023-05-16 | — | — | CN | disclosed |
| WO-2023081441-A1 | HETEROCYCLIC COMPOUNDS AND USES THEREOF | VENTUS THERAPEUTICS U.S., INC. (US) | 2023-05-11 | — | — | WO | disclosed |
| WO-2023067515-A1 | THIADIAZOLYL COMPOUNDS AS DNA POLYMERASE THETA INHIBITORS | IDEAYA BIOSCIENCES, INC. (US) | 2023-04-27 | — | — | WO | disclosed |
| CN-109071526-B | Acid addition salts of piperazine derivatives | 阿森纽荣股份公司 | 2023-02-28 | — | — | CN | disclosed |
| WO-2022259204-A1 | O-LINKED THIADIAZOLYL COMPOUNDS AS DNA POLYMERASE THETA INHIBITORS | IDEAYA BIOSCIENCES, INC. (US) | 2022-12-15 | — | — | WO | disclosed |
| CN-108884081-B | Process for separating enantiomers of piperazine derivatives | 阿森纽荣股份公司 | 2022-11-01 | — | — | CN | disclosed |
| CN-115109053-A | Thiazolesulfinyl thiadiazole derivative, intermediate, preparation method and application | 深圳湾实验室 | 2022-09-27 | — | — | CN | disclosed |
| WO-2022118210-A1 | SUBSTITUTED THIADIAZOLYL DERIVATIVES AS DNA POLYMERASE THETA INHIBITORS | IDEAYA BIOSCIENCES, INC. (US) | 2022-06-09 | — | — | WO | disclosed |
| US-20040244123-A1 | Dyeing composition for keratinous fibres comprising a particular dicationic diazo dye | L'OREAL S.A. (FR) | 2004-12-09 | — | — | US | disclosed |
| US-20040200009-A1 | Dyeing composition for keratinous fibers comprising a particular dicationic diazo dye | L'OREAL S.A. (FR) | 2004-10-14 | — | — | US | disclosed |
| EP-1416909-A2 | DYEING COMPOSITION FOR KERATINOUS FIBRES COMPRISING A PARTICULAR DICATIONIC DIAZO DYE | L'OREAL (FR) | 2004-05-12 | — | — | EP | disclosed |
| EP-1399425-A1 | DYEING COMPOSITION FOR KERATINOUS FIBRES COMPRISING A PARTICULAR DICATIONIC DIAZO DYE | L'OREAL (FR) | 2004-03-24 | — | — | EP | disclosed |
| WO-2002100369-A2 | DYEING COMPOSITION FOR KERATINOUS FIBRES COMPRISING A PARTICULAR DICATIONIC DIAZO DYE | L'OREAL (FR) | 2002-12-19 | — | — | WO | disclosed |
| WO-2002100834-A1 | DYEING COMPOSITION FOR KERATINOUS FIBRES COMPRISING A PARTICULAR DICATIONIC DIAZO DYE | L'OREAL (FR) | 2002-12-19 | — | — | WO | disclosed |
| EP-1181296-A1 | CELL ADHESION-INHIBITING ANTIINFLAMMATORY COMPOUNDS | ABBOTT LABORATORIES (US) | 2002-02-27 | — | — | EP | disclosed |
| EP-1090009-A2 | CELL ADHESION-INHIBITING ANTINFLAMMATORY COMPOUNDS | ABBOTT LABORATORIES (US) | 2001-04-11 | — | — | EP | disclosed |
| WO-2000075145-A1 | CELL ADHESION-INHIBITING ANTIINFLAMMATORY COMPOUNDS | ABBOTT LABORATORIES (US) | 2000-12-14 | — | — | WO | disclosed |
| WO-1999062908-A2 | CELL ADHESION-INHIBITING ANTINFLAMMATORY COMPOUNDS | ABBOTT LABORATORIES (US) | 1999-12-09 | — | — | WO | disclosed |