⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3639789 | 0.78 | — | — | |
| SCHEMBL675003 | 0.78 | — | — | |
| SCHEMBL18536324 | 0.78 | — | — | |
| SCHEMBL12514139 | 0.76 | — | — | |
| SCHEMBL18874694 | 0.75 | — | — | |
| SCHEMBL10975390 | 0.74 | — | — | |
| SCHEMBL10018115 | 0.74 | — | — | |
| SCHEMBL21428982 | 0.74 | — | — | |
| SCHEMBL3638407 | 0.74 | — | — | |
| SCHEMBL3638409 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11708347-B2 | Substituted benzofuran, benzopyrrole, benzothiophene, and structurally related complement inhibitors | BIOCRYST PHARMACEUTICALS, INC. (US) | 2023-07-25 | — | — | US | disclosed |
| EP-3778612-A1 | PHOSPHATE DERIVATIVES AND USE THEREOF | Zhu, Qing (CN) | 2021-02-17 | — | — | EP | disclosed |
| WO-2017155940-A1 | DNP AND DNP PRODRUG TREATMENT OF NEUROMUSCULAR, NEURODEGENERATIVE, AUTOIMMUNE, DEVELOPMENTAL, CONCUSSION, DRY EYE DISEASE, AND/OR METABOLIC DISEASES | Mitochon Pharmaceuticals, LLC (US) | 2017-09-14 | — | — | WO | disclosed |