⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19354825 | 0.77 | KMT2A (0.36) | — | |
| SCHEMBL20042526 | 0.77 | — | — | |
| SCHEMBL8543852 | 0.76 | KMT2A (0.33) | — | |
| SCHEMBL19354826 | 0.74 | PTGS1 (0.34) | — | |
| SCHEMBL7990000 | 0.74 | POLB (0.36) | — | |
| SCHEMBL5414431 | 0.72 | NPSR1 (0.51) | — | |
| SCHEMBL17190824 | 0.70 | — | — | |
| SCHEMBL18611070 | 0.70 | — | — | |
| SCHEMBL29011555 | 0.69 | PTGS1 (0.31) | — | |
| SCHEMBL28477581 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017155910-A1 | THIAZOLIDINONE COMPOUNDS AND USE THEREOF | NATIONAL HEALTH RESEARCH INSTITUTES (TW) | 2017-09-14 | — | — | WO | disclosed |