Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | ABL1 | P00519 | 1/20 | 0.37 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.37 |
| ▸ | MGAM | O43451 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | SI | P14410 | 1/20 | 0.35 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19321854 | 0.70 | TSHR (0.40) | TSHRHSD17B10CYP1A2ALDH1A1MAPT | |
| SCHEMBL12480441 | 0.69 | HTT (0.53) | TSHRHSD17B10CYP1A2ALDH1A1MAPT | |
| SCHEMBL6345936 | 0.68 | MAPT (0.41) | TSHRHSD17B10CYP1A2ALDH1A1MAPT | |
| SCHEMBL2257497 | 0.66 | KMT2A (0.41) | TSHRHSD17B10CYP1A2ALDH1A1KMT2A | |
| SCHEMBL11307625 | 0.66 | ITGB1 (0.55) | TSHRHSD17B10CYP1A2ALDH1A1MAPT | |
| SCHEMBL19322055 | 0.66 | TSHR (0.39) | TSHRHSD17B10CYP1A2ALDH1A1MAPT | |
| SCHEMBL3745667 | 0.66 | CYP1A2 (0.44) | TSHRHSD17B10CYP1A2ALDH1A1MAPT | |
| SCHEMBL10503347 | 0.65 | SMN1; SMN2 (0.54) | TSHRHSD17B10CYP1A2ALDH1A1MAPT | |
| Water SCHEMBL9787126 | 0.65 | CYP2D6 (0.47) | CYP1A2ALDH1A1MAPTKMT2APOLB | |
| SCHEMBL19321853 | 0.64 | TSHR (0.38) | TSHRHSD17B10CYP1A2ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017155910-A1 | THIAZOLIDINONE COMPOUNDS AND USE THEREOF | NATIONAL HEALTH RESEARCH INSTITUTES (TW) | 2017-09-14 | — | — | WO | disclosed |