Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | HTR7 | P34969 | 2/20 | 0.49 |
| ▸ | PHLPP2 | Q6ZVD8 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | DRD3 | P35462 | 2/20 | 0.42 |
| ▸ | SCN1A | P35498 | 2/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.42 |
| ▸ | SCN2A | Q99250 | 2/20 | 0.42 |
| ▸ | SCN3A | Q9NY46 | 2/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19354881 | 0.92 | PHLPP2 (0.56) | GAAALDH1A1HTR7PHLPP2MAPK1 | |
| SCHEMBL19317264 | 0.90 | GAA (0.57) | GAAALDH1A1HTR7PHLPP2MAPK1 | |
| SCHEMBL19321968 | 0.83 | GAA (0.64) | GAAALDH1A1HTR7PHLPP2MAPK1 | |
| SCHEMBL19317266 | 0.82 | PHLPP2 (0.55) | GAAALDH1A1HTR7PHLPP2MAPK1 | |
| SCHEMBL9629064 | 0.78 | GAA (0.84) | GAAALDH1A1PHLPP2MAPK1HSD17B10 | |
| SCHEMBL14924442 | 0.75 | GAA (0.74) | GAAALDH1A1PHLPP2MAPK1LMNA | |
| SCHEMBL29024895 | 0.75 | GAA (0.51) | GAAALDH1A1HTR7PHLPP2MAPK1 | |
| SCHEMBL19317333 | 0.75 | ESR1 (0.60) | ALDH1A1MAPK1LMNACYP1A2CYP3A4 | |
| SCHEMBL19354600 | 0.75 | CHRM5 (0.39) | LMNACYP1A2ESR1POLBMAPT | |
| SCHEMBL19321966 | 0.74 | PHLPP2 (0.62) | GAAALDH1A1HTR7PHLPP2MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017155910-A1 | THIAZOLIDINONE COMPOUNDS AND USE THEREOF | NATIONAL HEALTH RESEARCH INSTITUTES (TW) | 2017-09-14 | — | — | WO | disclosed |