Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.41 |
| ▸ | HTT | P42858 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.40 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.40 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.40 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.40 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.40 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.38 |
| ▸ | FOLH1 | Q04609 | 4/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | FAAH | O00519 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22459523 | 0.87 | SMN1; SMN2 (0.40) | SMN1; SMN2HTTHPGDHDAC1HDAC3 | |
| SCHEMBL24822610 | 0.86 | SMN1; SMN2 (0.43) | SMN1; SMN2HTTHPGDHDAC1HDAC3 | |
| SCHEMBL23515744 | 0.83 | SMN1; SMN2 (0.47) | SMN1; SMN2HPGDHDAC1HDAC3HDAC4 | |
| SCHEMBL22989393 | 0.82 | HDAC1 (0.42) | SMN1; SMN2HTTHPGDHDAC1HDAC3 | |
| SCHEMBL22476493 | 0.82 | HDAC1 (0.40) | SMN1; SMN2HTTHPGDHDAC1HDAC3 | |
| SCHEMBL14670750 | 0.82 | HDAC1 (0.37) | SMN1; SMN2HTTHPGDHDAC1HDAC3 | |
| SCHEMBL22456058 | 0.81 | SMN1; SMN2 (0.36) | SMN1; SMN2HTTHPGDHDAC1HDAC3 | |
| SCHEMBL17896922 | 0.81 | SMN1; SMN2 (0.36) | SMN1; SMN2HTTHPGDHDAC1HDAC3 | |
| SCHEMBL10283656 | 0.81 | HPGD (0.50) | SMN1; SMN2HTTHPGDHDAC1HDAC3 | |
| SCHEMBL19704167 | 0.81 | SMN1; SMN2 (0.50) | SMN1; SMN2HTTHPGDHDAC1HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017153432-A1 | A NEW UNIVERSAL METHOD TO CAPTURE AND ANALYZE ADCS FOR CHARACTERIZATION OF DRUG DISTRIBUTION AND THE DRUG-TO-ANTIBODY RATIO IN BIOLOGICAL SAMPLES | PIERRE FABRE MEDICAMENT (FR) | 2017-09-14 | — | — | WO | disclosed |