Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MST1R | Q04912 | 18/20 | 0.55 |
| ▸ | MET | P08581 | 2/20 | 0.52 |
| ▸ | KDR | P35968 | 2/20 | 0.52 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.52 |
| ▸ | KIT | P10721 | 1/20 | 0.52 |
| ▸ | AXL | P30530 | 1/20 | 0.52 |
| ▸ | FLT3 | P36888 | 1/20 | 0.52 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1934621 | 0.96 | MST1R (0.56) | MST1RMETKDRNTRK1KIT | |
| SCHEMBL14849177 | 0.91 | MST1R (0.55) | MST1RMETKDRNTRK1KIT | |
| SCHEMBL1478490 | 0.91 | MST1R (0.54) | MST1RMETKDRNTRK1KIT | |
| SCHEMBL2533116 | 0.90 | MST1R (0.57) | MST1RMETKDRNTRK1KIT | |
| SCHEMBL2539215 | 0.90 | MST1R (0.55) | MST1RMETKDRNTRK1KIT | |
| SCHEMBL14839358 | 0.89 | MST1R (0.53) | MST1RMETKDRNTRK1KIT | |
| SCHEMBL2538054 | 0.89 | MST1R (0.57) | MST1RMETKDRNTRK1KIT | |
| SCHEMBL2534301 | 0.88 | MST1R (0.54) | MST1RMETKDRNTRK1KIT | |
| SCHEMBL2534298 | 0.88 | MST1R (0.54) | MST1RMETKDRNTRK1KIT | |
| SCHEMBL1478769 | 0.88 | MST1R (0.65) | MST1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2332536-A1 | Inhibitors of protein tyrosine kinase activity | MethylGene Inc. (CA) | 2011-06-15 | — | — | EP | disclosed |