⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18112614 | 0.83 | — | — | |
| SCHEMBL18112612 | 0.83 | — | — | |
| SCHEMBL18112615 | 0.83 | — | — | |
| SCHEMBL1937444 | 0.82 | KDM4E (0.30) | — | |
| SCHEMBL1937442 | 0.82 | KDM4E (0.30) | — | |
| SCHEMBL18112605 | 0.82 | — | — | |
| SCHEMBL18112604 | 0.82 | — | — | |
| SCHEMBL1935674 | 0.80 | — | — | |
| SCHEMBL3121312 | 0.78 | RECQL (0.34) | — | |
| SCHEMBL13033936 | 0.78 | CHRNA1 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016155831-A1 | ISOXAZOLINE-STYRENE DERIVATIVES AS INSECTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2016-10-06 | — | — | WO | disclosed |
| WO-2016155831-A1 | ISOXAZOLINE-STYRENE DERIVATIVES AS INSECTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2016-10-06 | — | — | WO | disclosed |
| US-9216973-B2 | Insecticidal compounds | SYNGENTA PARTICIPATIONS AG (CH) | 2015-12-22 | — | — | US | disclosed |
| US-9216973-B2 | Insecticidal compounds | SYNGENTA PARTICIPATIONS AG (CH) | 2015-12-22 | — | — | US | disclosed |
| US-9216973-B2 | Insecticidal compounds | SYNGENTA PARTICIPATIONS AG (CH) | 2015-12-22 | — | — | US | disclosed |
| EP-2331536-B1 | INSECTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2013-08-21 | — | — | EP | disclosed |
| EP-2331536-B1 | INSECTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2013-08-21 | — | — | EP | disclosed |
| US-20130165485-A1 | INSECTICIDAL COMPOUNDS | SYNGENTA CROP PROTECTION LLC (US) | 2013-06-27 | — | — | US | disclosed |
| US-20130165485-A1 | INSECTICIDAL COMPOUNDS | SYNGENTA CROP PROTECTION LLC (US) | 2013-06-27 | — | — | US | disclosed |
| US-20130165485-A1 | INSECTICIDAL COMPOUNDS | SYNGENTA CROP PROTECTION LLC (US) | 2013-06-27 | — | — | US | disclosed |
| US-20110269804-A1 | INSECTICIDAL COMPOUNDS | SYNGENTA CROP PROTECTION LLC (US) | 2011-11-03 | — | — | US | disclosed |
| US-20110269804-A1 | INSECTICIDAL COMPOUNDS | SYNGENTA CROP PROTECTION LLC (US) | 2011-11-03 | — | — | US | disclosed |
| US-20110269804-A1 | INSECTICIDAL COMPOUNDS | SYNGENTA CROP PROTECTION LLC (US) | 2011-11-03 | — | — | US | disclosed |
| EP-2331536-A1 | INSECTICIDAL COMPOUNDS | Syngenta Participations AG (CH) | 2011-06-15 | — | — | EP | disclosed |
| WO-2010020522-A1 | INSECTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2010-02-25 | — | — | WO | disclosed |
| WO-2010020522-A1 | INSECTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2010-02-25 | — | — | WO | disclosed |