Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 2/20 | 0.73 |
| ▸ | EGFR | P00533 | 1/20 | 0.66 |
| ▸ | HTR1A | P08908 | 2/20 | 0.64 |
| ▸ | HTR2C | P28335 | 2/20 | 0.64 |
| ▸ | HTR2A | P28223 | 1/20 | 0.64 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.64 |
| ▸ | HTR7 | P34969 | 1/20 | 0.64 |
| ▸ | HTR6 | P50406 | 1/20 | 0.64 |
| ▸ | TYR | P14679 | 1/20 | 0.53 |
| ▸ | PYGL | P06737 | 4/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19369316 | 1.00 | APP (0.73) | APPEGFRHTR1AHTR2CHTR2A | |
| SCHEMBL19359032 | 0.86 | APP (0.97) | APPEGFRTYR | |
| SCHEMBL19369312 | 0.86 | APP (0.97) | APPEGFRTYR | |
| SCHEMBL19359011 | 0.86 | APP (0.97) | APPEGFRTYR | |
| SCHEMBL19369578 | 0.86 | APP (0.97) | APPEGFRTYR | |
| SCHEMBL16382868 | 0.86 | APP (0.97) | APPEGFRTYR | |
| SCHEMBL8757074 | 0.86 | APP (0.97) | APPEGFRTYR | |
| SCHEMBL19369579 | 0.86 | APP (0.97) | APPEGFRTYR | |
| Caffeoylhexylamide SCHEMBL16382873 | 0.86 | APP (0.97) | APPEGFRTYR | |
| SCHEMBL875397 | 0.86 | APP (0.97) | APPEGFRTYR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017161093-A1 | CAFFEIC ACID DERIVATIVES AND USES THEREOF | MUSC FOUNDATION FOR RESEARCH DEVELOPMENT (US) | 2017-09-21 | — | — | WO | claimed |