Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 8/20 | 0.72 |
| ▸ | TTR | P02766 | 1/20 | 0.51 |
| ▸ | DPP4 | P27487 | 1/20 | 0.51 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.50 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | FDPS | P14324 | 1/20 | 0.48 |
| ▸ | CA12 | O43570 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | CA7 | P43166 | 1/20 | 0.48 |
| ▸ | CA9 | Q16790 | 1/20 | 0.48 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19359027 | 1.00 | APP (0.72) | APPTTRDPP4HCAR2ALOX5 | |
| SCHEMBL14727949 | 0.90 | APP (0.81) | APPTTRDPP4 | |
| SCHEMBL28884853 | 0.88 | APP (0.68) | APPTTRDPP4HCAR2ALOX5 | |
| SCHEMBL10482468 | 0.87 | APP (0.76) | APPHCAR2HTTSMN1; SMN2CA12 | |
| SCHEMBL27627337 | 0.85 | APP (0.66) | APPHCAR2ALOX5HTTSMN1; SMN2 | |
| SCHEMBL17321170 | 0.85 | APP (0.66) | APPHCAR2ALOX5HTTSMN1; SMN2 | |
| SCHEMBL974015 | 0.85 | APP (0.69) | APPHCAR2HTTSMN1; SMN2CA12 | |
| SCHEMBL9243655 | 0.85 | APP (0.69) | APPHCAR2HTTSMN1; SMN2CA12 | |
| SCHEMBL11266625 | 0.84 | TTR (0.69) | APPTTRDPP4ALOX5SMN1; SMN2 | |
| SCHEMBL11266626 | 0.84 | TTR (0.69) | APPTTRDPP4ALOX5SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017161093-A1 | CAFFEIC ACID DERIVATIVES AND USES THEREOF | MUSC FOUNDATION FOR RESEARCH DEVELOPMENT (US) | 2017-09-21 | — | — | WO | claimed |
| WO-2017161093-A1 | CAFFEIC ACID DERIVATIVES AND USES THEREOF | MUSC FOUNDATION FOR RESEARCH DEVELOPMENT (US) | 2017-09-21 | — | — | WO | disclosed |