Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PAOX | Q6QHF9 | 3/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | F13A1 | P00488 | 1/20 | 0.35 |
| ▸ | MTNR1A | P48039 | 4/20 | 0.34 |
| ▸ | MTNR1B | P49286 | 4/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL9299355 | 0.91 | PAOX (0.52) | PAOXKDM4EMAPK1HIF1ATSHR | |
| SCHEMBL474178 | 0.90 | — | — | |
| SCHEMBL20768364 | 0.90 | KDM4E (0.57) | PAOXKDM4EMAPK1HIF1ATSHR | |
| Hydrogen Sulfide SCHEMBL19359044 | 0.87 | — | — | |
| SCHEMBL22361778 | 0.87 | KDM4E (0.55) | PAOXKDM4EMAPK1HIF1ATSHR | |
| Ammonia Solution, Strong SCHEMBL28356491 | 0.87 | — | — | |
| SCHEMBL10545704 | 0.87 | — | — | |
| Hydrochloric Acid SCHEMBL3979349 | 0.87 | — | — | |
| SCHEMBL10545165 | 0.87 | — | — | |
| Ethyl Chloride SCHEMBL29164065 | 0.81 | KDM4E (0.48) | PAOXKDM4EMAPK1HIF1ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117599029-A | Compositions for controlled release of cysteamine and systematic treatment of cysteamine-sensitive disorders | 硫创治疗公司 | 2024-02-27 | — | — | CN | disclosed |
| US-11786491-B2 | Compositions for controlled release of cysteamine and systemic treatment of cysteamine sensitive disorders | THIOGENESIS THERAPEUTICS, INC. (US) | 2023-10-17 | — | — | US | disclosed |
| US-20220040127-A1 | COMPOSITIONS FOR CONTROLLED RELEASE OF CYSTEAMINE AND SYSTEMIC TREATMENT OF CYSTEAMINE SENSITIVE DISORDERS | THIOGENESIS THERAPEUTICS, INC. | 2022-02-10 | — | — | US | disclosed |
| US-11173135-B2 | Compositions for controlled release of cysteamine and systemic treatment of cysteamine sensitive disorders | THIOGENESIS THERAPEUTICS, INC. (US) | 2021-11-16 | — | — | US | disclosed |
| US-20190070132-A1 | COMPOSITIONS FOR CONTROLLED RELEASE OF CYSTEAMINE AND SYSTEMIC TREATMENT OF CYSTEAMINE SENSITIVE DISORDERS | THIOGENESIS THERAPEUTICS, INC. | 2019-03-07 | — | — | US | disclosed |
| EP-3429573-A1 | COMPOSITIONS FOR CONTROLLED RELEASE OF CYSTEAMINE AND SYSTEMIC TREATMENT OF CYSTEAMINE SENSITIVE DISORDERS | Thiogenesis Therapeutics, Inc. (US) | 2019-01-23 | — | — | EP | disclosed |
| WO-2017161318-A1 | COMPOSITIONS FOR CONTROLLED RELEASE OF CYSTEAMINE AND SYSTEMIC TREATMENT OF CYSTEAMINE SENSITIVE DISORDERS | THIOGENESIS THERAPEUTICS, INC. (US) | 2017-09-21 | — | — | WO | disclosed |