Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 20/20 | 0.72 |
| ▸ | PIK3R2 | O00459 | 6/20 | 0.56 |
| ▸ | PIK3CG | P48736 | 5/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17458098 | 0.83 | PIK3CD (1.00) | PIK3CDPIK3R2PIK3CG | |
| SCHEMBL17458095 | 0.83 | PIK3CD (1.00) | PIK3CDPIK3R2PIK3CG | |
| SCHEMBL17458057 | 0.83 | PIK3CD (1.00) | PIK3CDPIK3R2 | |
| SCHEMBL17458060 | 0.83 | PIK3CD (1.00) | PIK3CDPIK3R2 | |
| SCHEMBL17458047 | 0.83 | PIK3CD (1.00) | PIK3CDPIK3R2PIK3CG | |
| SCHEMBL17461935 | 0.83 | PIK3CD (1.00) | PIK3CDPIK3R2PIK3CG | |
| SCHEMBL17458044 | 0.83 | PIK3CD (1.00) | PIK3CDPIK3R2PIK3CG | |
| SCHEMBL23912374 | 0.80 | PIK3CD (0.70) | PIK3CDPIK3R2PIK3CG | |
| SCHEMBL19941899 | 0.76 | PIK3CD (0.72) | PIK3CDPIK3CG | |
| SCHEMBL15815362 | 0.74 | PIK3CD (0.81) | PIK3CDPIK3CG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9765060-B2 | Phosphatidylinositol 3-kinase inhibitors | GILEAD SCIENCES, INC. (US) | 2017-09-19 | — | — | US | disclosed |