Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | ACE | P12821 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | THPO | P40225 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | PSMB5 | P28074 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13857484 | 0.83 | CYP2C9 (0.43) | CYP2C9PSMB5MEN1KMT2ANPC1 | |
| SCHEMBL19155933 | 0.82 | CYP2C9 (0.39) | CYP2C9PSMB5MEN1KMT2ANPC1 | |
| SCHEMBL13122874 | 0.80 | CYP2C9 (0.41) | CYP2C9NFKB1PSMB5MEN1KMT2A | |
| SCHEMBL14131182 | 0.80 | CYP2C9 (0.41) | CYP2C9NFKB1PSMB5MEN1KMT2A | |
| SCHEMBL1804546 | 0.79 | KDM4E (0.63) | CYP2C9ACEKDM4EMAPTTHRB | |
| SCHEMBL22657901 | 0.79 | KDM4E (0.63) | CYP2C9ACEKDM4EMAPTTHRB | |
| SCHEMBL13402412 | 0.79 | KDM4E (0.47) | CYP2C9ACEKDM4EMAPTTHRB | |
| SCHEMBL1804545 | 0.79 | KDM4E (0.63) | CYP2C9ACEKDM4EMAPTTHRB | |
| SCHEMBL16749939 | 0.79 | CYP2C9 (0.43) | CYP2C9ACEKDM4EMAPTTHRB | |
| SCHEMBL16549458 | 0.79 | KDM4E (0.63) | ACEKDM4EMAPTTHRBALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019005966-A1 | DENDRIMER DRUG CONJUGATES FOR SUSTAINED INTRA-ARTICULAR DELIVERY | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2019-01-03 | — | — | WO | disclosed |
| US-9764037-B2 | Conjugate compounds | VICTORIA LINK LIMITED (NZ) | 2017-09-19 | — | — | US | disclosed |