Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 4/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | NQO2 | P16083 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29595828 | 0.83 | NOTUM (0.43) | NOTUMMAPK1NQO2ALDH1A1MRGPRX4 | |
| SCHEMBL15633295 | 0.83 | NOTUM (0.43) | NOTUMMAPK1NQO2ALDH1A1MRGPRX4 | |
| SCHEMBL15633243 | 0.81 | NOTUM (0.42) | NOTUMMAPK1NQO2ALDH1A1MRGPRX4 | |
| SCHEMBL20321125 | 0.81 | MAPK1 (0.43) | MAPK1ALDH1A1ATM | |
| SCHEMBL24386910 | 0.80 | NOTUM (0.43) | NOTUMMAPK1NQO2ALDH1A1MRGPRX4 | |
| SCHEMBL17440068 | 0.76 | NQO2 (0.48) | NOTUMMAPK1NQO2ALDH1A1MRGPRX4 | |
| SCHEMBL18725396 | 0.76 | NQO2 (0.46) | NOTUMMAPK1NQO2ALDH1A1MRGPRX4 | |
| SCHEMBL3936135 | 0.73 | MAPK1 (0.47) | NOTUMMAPK1NQO2ALDH1A1ATM | |
| SCHEMBL30031450 | 0.73 | MAPK1 (0.47) | NOTUMMAPK1NQO2ALDH1A1ATM | |
| SCHEMBL19835436 | 0.72 | MAPK1 (0.50) | NOTUMMAPK1NQO2ALDH1A1MRGPRX4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2903977-B1 | 5-PHENOXY-3H-PYRIMIDIN-4-ONE DERIVATIVES AND THEIR USE AS HIV REVERSE TRANSCRIPTASE INHIBITORS | MERCK SHARP & DOHME (US) | 2017-09-20 | — | — | EP | disclosed |