Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.43 |
| ▸ | GRM5 | P41594 | 5/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | CHKA | P35790 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | NPY2R | P49146 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | DRD4 | P21917 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | FAAH | O00519 | 1/20 | 0.39 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16238221 | 0.94 | GRM5 (0.42) | TRPV1GRM5MEN1KMT2ACHKA | |
| SCHEMBL17778336 | 0.94 | GRM5 (0.42) | TRPV1GRM5MEN1KMT2ACHKA | |
| SCHEMBL16238325 | 0.94 | GRM5 (0.42) | TRPV1GRM5MEN1KMT2ACHKA | |
| SCHEMBL17618737 | 0.84 | CNR2 (0.52) | TRPV1GRM5KMT2ACNR2 | |
| SCHEMBL17618761 | 0.82 | CNR2 (0.40) | TRPV1GRM5MEN1KMT2ANPY2R | |
| SCHEMBL17775617 | 0.81 | TRPV1 (0.39) | TRPV1GRM5MEN1KMT2ADRD2 | |
| SCHEMBL16237541 | 0.81 | KMT2A (0.38) | MEN1KMT2AFAAH | |
| SCHEMBL17777056 | 0.81 | MEN1 (0.41) | TRPV1GRM5MEN1KMT2ACHKA | |
| SCHEMBL16754464 | 0.81 | TRPV1 (0.39) | TRPV1GRM5MEN1KMT2ADRD2 | |
| SCHEMBL16754508 | 0.81 | KMT2A (0.38) | MEN1KMT2AFAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9765075-B2 | Substituted bridged urea analogs as sirtuin modulators | GLAXOSMITHKLINE LLC (US) | 2017-09-19 | — | — | US | disclosed |