Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 2/20 | 0.52 |
| ▸ | BRAF | P15056 | 15/20 | 0.47 |
| ▸ | LYN | P07948 | 1/20 | 0.41 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.41 |
| ▸ | GSK3A | P49840 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1935902 | 0.92 | MAPK14 (0.53) | MAPK14BRAFGSK3A | |
| SCHEMBL1936602 | 0.92 | MAPK14 (0.56) | MAPK14BRAFGSK3A | |
| SCHEMBL1935710 | 0.92 | MAPK14 (0.54) | MAPK14BRAF | |
| SCHEMBL2671044 | 0.91 | MAPK14 (0.53) | MAPK14BRAFLYNMAPK9GSK3A | |
| SCHEMBL1934591 | 0.91 | MAPK14 (0.53) | MAPK14BRAFGSK3A | |
| SCHEMBL15063056 | 0.91 | MAPK14 (0.53) | MAPK14BRAFGSK3A | |
| SCHEMBL1934414 | 0.91 | MAPK14 (0.53) | MAPK14BRAFGSK3A | |
| SCHEMBL1936434 | 0.88 | MAPK14 (0.55) | MAPK14BRAFLYNMAPK9 | |
| Trifluoroacetic Acid SCHEMBL2671436 | 0.86 | MAPK14 (0.53) | MAPK14BRAFLYNMAPK9GSK3A | |
| SCHEMBL2671560 | 0.83 | MAPK14 (0.54) | MAPK14BRAFLYNMAPK9GSK3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2331506-B1 | NOVEL BENZAMIDES, PRODUCTION THEREOF, AND USE THEREOF AS MEDICAMENTS | BOEHRINGER INGELHEIM INT (DE) | 2013-07-03 | — | — | EP | disclosed |
| EP-2331506-A1 | NOVEL BENZAMIDES, PRODUCTION THEREOF, AND USE THEREOF AS MEDICAMENTS | Boehringer Ingelheim International GmbH (DE) | 2011-06-15 | — | — | EP | disclosed |
| WO-2010026095-A1 | NOVEL BENZAMIDES, PRODUCTION THEREOF, AND USE THEREOF AS MEDICAMENTS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2010-03-11 | — | — | WO | disclosed |