Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNJ1 | P48048 | 20/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19367052 | 1.00 | KCNJ1 (0.56) | KCNJ1 | |
| SCHEMBL15036668 | 1.00 | KCNJ1 (0.56) | KCNJ1 | |
| SCHEMBL14726141 | 1.00 | KCNJ1 (0.56) | KCNJ1 | |
| SCHEMBL15956456 | 1.00 | KCNJ1 (0.56) | KCNJ1 | |
| SCHEMBL15036613 | 1.00 | KCNJ1 (0.56) | KCNJ1 | |
| SCHEMBL14721997 | 1.00 | KCNJ1 (0.56) | KCNJ1 | |
| Hydrochloric Acid SCHEMBL15878853 | 0.99 | KCNJ1 (0.56) | KCNJ1 | |
| Hydrochloric Acid SCHEMBL15878932 | 0.99 | KCNJ1 (0.56) | KCNJ1 | |
| Hydrochloric Acid SCHEMBL16227677 | 0.99 | KCNJ1 (0.56) | KCNJ1 | |
| Hydrochloric Acid SCHEMBL16227827 | 0.99 | KCNJ1 (0.56) | KCNJ1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2934533-B1 | INHIBITORS OF THE RENAL OUTER MEDULLARY POTASSIUM CHANNEL | MERCK SHARP & DOHME (US) | 2017-11-15 | — | — | EP | disclosed |
| EP-2956142-B1 | INHIBITORS OF THE RENAL OUTER MEDULLARY POTASSIUM CHANNEL | MERCK SHARP & DOHME (US) | 2017-09-20 | — | — | EP | disclosed |