⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24073037 | 0.78 | — | — | |
| SCHEMBL20910881 | 0.77 | AKR1C3 (0.52) | — | |
| SCHEMBL337228 | 0.74 | — | — | |
| SCHEMBL1832720 | 0.74 | — | — | |
| SCHEMBL4342558 | 0.73 | — | — | |
| SCHEMBL24904293 | 0.73 | — | — | |
| SCHEMBL983744 | 0.72 | — | — | |
| SCHEMBL1202767 | 0.72 | — | — | |
| SCHEMBL429044 | 0.72 | — | — | |
| SCHEMBL983745 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10882861-B2 | Purine nucleotide derivatives | THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (US) | 2021-01-05 | — | — | US | claimed |
| US-20190300532-A1 | PURINE NUCLEOTIDE DERIVATIVES | THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (US) | 2019-10-03 | — | — | US | claimed |
| WO-2017201382-A1 | PURINE NUCLEOTIDE DERIVATIVES | THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (US) | 2017-11-23 | — | — | WO | claimed |
| US-20260109989-A1 | COMPOSITIONS AND METHODS FOR THE SYNTHESIS AND IDENTIFICATION OF COVALENT APTAMERS | UNIV HAWAII (US) | 2026-04-23 | — | — | US | disclosed |
| US-12371694-B2 | Compositions and methods for the synthesis and identification of covalent aptamers | UNIVERSITY OF HAWAII (US) | 2025-07-29 | — | — | US | disclosed |
| EP-4441066-A1 | SYNTHESIS OF 2' ACETYL-ESTER PROTECTED NUCLEOSIDES | Hongene Biotech Corporation (US) | 2024-10-09 | — | — | EP | disclosed |
| CN-118317970-A | Synthesis of 2' acetyl-ester protected nucleosides | 兆维生物科技公司 | 2024-07-09 | — | — | CN | disclosed |
| US-11897914-B2 | Synthesis of 2′ protected nucleosides | HONGENE BIOTECH CORPORATION (US) | 2024-02-13 | — | — | US | disclosed |
| EP-4298104-A1 | HYDROCINNAMOYL PROTECTED RIBOGUANOSINE PHOSPHORAMIDITES FOR DECREASING DEPYRIMIDINATION FROM ALKYL AMINE EXPOSURE DURING FINAL DEPROTECTION | Agilent Technologies, Inc. (US) | 2024-01-03 | — | — | EP | disclosed |
| US-20230416295-A1 | SYNTHESIS OF 2' PROTECTED NUCLEOSIDES | HONGENE BIOTECH CORPORATION | 2023-12-28 | — | — | US | disclosed |
| CN-116981676-A | Cyano-protected riboguanosine phosphoramidites for reducing depyrimidition caused by alkylamine exposure during final deprotection | 安捷伦科技有限公司 | 2023-10-31 | — | — | CN | disclosed |
| US-20220275019-A1 | HYDROCINNAMOYL PROTECTED RIBOGUANOSINE PHOSPHORAMIDITES FOR DECREASING DEPYRIMIDINATION FROM ALKYL AMINE EXPOSURE DURING FINAL DEPROTECTION | AGILENT TECHNOLOGIES, INC. | 2022-09-01 | — | — | US | disclosed |
| US-20210395742-A1 | COMPOSITIONS AND METHODS FOR THE SYNTHESIS AND IDENTIFICATION OF COVALENT APTAMERS | UNIVERSITY OF HAWAII | 2021-12-23 | — | — | US | disclosed |
| US-10882861-B2 | Purine nucleotide derivatives | THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (US) | 2021-01-05 | — | — | US | disclosed |
| WO-2020102287-A1 | COMPOSITIONS AND METHODS FOR THE SYNTHESIS AND IDENTIFICATION OF COVALENT APTAMERS | UNIVERSITY OF HAWAII (US) | 2020-05-22 | — | — | WO | disclosed |
| US-20190300532-A1 | PURINE NUCLEOTIDE DERIVATIVES | THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (US) | 2019-10-03 | — | — | US | disclosed |
| US-9896472-B2 | Protected monomer and method of final deprotection for RNA synthesis | AGILENT TECHNOLOGIES, INC. (US) | 2018-02-20 | — | — | US | disclosed |
| WO-2017201382-A1 | PURINE NUCLEOTIDE DERIVATIVES | THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (US) | 2017-11-23 | — | — | WO | disclosed |
| US-20160002282-A1 | Protected Monomer and Method of Final Deprotection for RNA Synthesis | AGILENT TECHNOLOGIES, INC. | 2016-01-07 | — | — | US | disclosed |
| EP-2331558-A2 | PROTECTED MONOMERS AND METHODS OF DEPROTECTION FOR RNA SYNTHESIS | Agilent Technologies, Inc. (US) | 2011-06-15 | — | — | EP | disclosed |