Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK1E | P49674 | 6/20 | 0.54 |
| ▸ | PIM1 | P11309 | 3/20 | 0.37 |
| ▸ | ZAP70 | P43403 | 3/20 | 0.36 |
| ▸ | PRKD1 | Q15139 | 2/20 | 0.36 |
| ▸ | PRKD2 | Q9BZL6 | 2/20 | 0.36 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.36 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.36 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.35 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1937484 | 1.00 | CSNK1E (0.54) | CSNK1EPIM1ZAP70PRKD1PRKD2 | |
| SCHEMBL477091 | 0.90 | CSNK1E (0.54) | CSNK1EPIM1ZAP70PRKD1PRKD2 | |
| SCHEMBL477092 | 0.90 | CSNK1E (0.54) | CSNK1EPIM1ZAP70PRKD1PRKD2 | |
| SCHEMBL477176 | 0.87 | CSNK1E (0.69) | CSNK1E | |
| SCHEMBL477143 | 0.87 | CSNK1E (0.69) | CSNK1E | |
| SCHEMBL477023 | 0.83 | CSNK1E (0.59) | CSNK1EPIM1 | |
| SCHEMBL477025 | 0.83 | CSNK1E (0.59) | CSNK1EPIM1 | |
| SCHEMBL477061 | 0.80 | CSNK1E (0.73) | CSNK1E | |
| SCHEMBL477060 | 0.80 | CSNK1E (0.73) | CSNK1E | |
| SCHEMBL477034 | 0.77 | CSNK1E (0.59) | CSNK1EPIM1ZAP70PRKD1PRKD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2331546-A1 | 2-ALKYL-6-CYCLOAMINO-3-(PYRIDIN-4-YL)IMIDAZO[1,2-IB]-PYRIDAZINE DERIVATIVES, PREPARATION THEREOF, AND THERAPEUTIC APPLICATION THEREOF | Sanofi-aventis (FR) | 2011-06-15 | — | — | EP | claimed |
| WO-2010018327-A1 | 2-ALKYL-6-CYCLOAMINO-3-(PYRIDIN-4-YL)IMIDAZO[1,2-IB]-PYRIDAZINE DERIVATIVES, PREPARATION THEREOF, AND THERAPEUTIC APPLICATION THEREOF | SANOFI-AVENTIS (FR) | 2010-02-18 | — | — | WO | claimed |