Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | PDE6D | O43924 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.32 |
| ▸ | AGTR1 | P30556 | 3/20 | 0.32 |
| ▸ | AGTR2 | P50052 | 3/20 | 0.32 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.32 |
| ▸ | CASR | P41180 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | RECQL | P46063 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20432436 | 0.77 | MDM2 (0.35) | ALDH1A1KMT2AMEN1MDM2 | |
| SCHEMBL18834615 | 0.74 | KMT2A (0.33) | ALDH1A1KMT2AMEN1MDM2CASR | |
| SCHEMBL18834164 | 0.72 | MDM2 (0.39) | MDM2LMNA | |
| SCHEMBL20432461 | 0.71 | KDM4E (0.34) | ALDH1A1KMT2AMEN1LMNASMN1; SMN2 | |
| SCHEMBL18833628 | 0.66 | PPARG (0.33) | ALDH1A1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL19375389 | 0.64 | TLR7 (0.33) | ALDH1A1KMT2AMEN1TLR7AGTR1 | |
| SCHEMBL19375249 | 0.64 | PLK4 (0.36) | KMT2AMEN1MDM2SMN1; SMN2 | |
| SCHEMBL18833791 | 0.63 | PDE4A (0.45) | TLR7AGTR1AGTR2 | |
| SCHEMBL19375251 | 0.61 | MDM2 (0.39) | ALDH1A1MDM2 | |
| SCHEMBL20432384 | 0.61 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2970303-B9 | SUBSTITUTED XANTHINES AND METHODS OF USE THEREOF | HYDRA BIOSCIENCES INC (US) | 2017-09-20 | — | — | EP | disclosed |