Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 13/20 | 0.65 |
| ▸ | ABL1 | P00519 | 4/20 | 0.65 |
| ▸ | HCK | P08631 | 1/20 | 0.65 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.53 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.53 |
| ▸ | FYN | P06241 | 1/20 | 0.53 |
| ▸ | PRKACA | P17612 | 1/20 | 0.53 |
| ▸ | CDK2 | P24941 | 1/20 | 0.53 |
| ▸ | CSK | P41240 | 1/20 | 0.53 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.53 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.53 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.53 |
| ▸ | PRKD1 | Q15139 | 1/20 | 0.53 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.53 |
| ▸ | PRKD2 | Q9BZL6 | 1/20 | 0.53 |
| ▸ | CDK12 | Q9NYV4 | 1/20 | 0.53 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.53 |
| ▸ | CMA1 | P23946 | 2/20 | 0.41 |
| ▸ | EGFR | P00533 | 2/20 | 0.38 |
| ▸ | RET | P07949 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19375751 | 0.88 | SRC (0.73) | SRCABL1HCKRIPK2PRKD3 | |
| SCHEMBL19376526 | 0.87 | SRC (0.73) | SRCABL1HCKRIPK2PRKD3 | |
| SCHEMBL29391118 | 0.84 | SRC (0.76) | SRCABL1HCKRIPK2PRKD3 | |
| SCHEMBL12437019 | 0.84 | SRC (0.76) | SRCABL1HCKRIPK2PRKD3 | |
| SCHEMBL12437015 | 0.83 | SRC (0.64) | SRCABL1HCKRIPK2PRKD3 | |
| SCHEMBL29390309 | 0.83 | SRC (0.64) | SRCABL1HCKRIPK2PRKD3 | |
| SCHEMBL12436004 | 0.82 | SRC (0.77) | SRCABL1HCKRIPK2PRKD3 | |
| SCHEMBL29390927 | 0.82 | SRC (0.77) | SRCABL1HCKRIPK2PRKD3 | |
| SCHEMBL22224482 | 0.80 | SRC (0.59) | SRCABL1HCKRIPK2PRKD3 | |
| SCHEMBL12436152 | 0.80 | SRC (1.00) | SRCABL1HCKRIPK2PRKD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9765037-B2 | Compositions and methods for treating toxoplasmosis, cryptosporidiosis, and other apicomplexan protozoan related diseases | UNIVERSITY OF WASHINGTON THROUGH ITS CENTER FOR COMMERCIALIZATION (US) | 2017-09-19 | — | — | US | disclosed |