SCHEMBL19381706

SCHEMBL19381706

C=C(C)c1cc(Oc2nc(O)c3ccncc3n2)ccc1N(C)c1ccc(C(C)C)cc1

nearest known ligand 0.51

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ KDM4C Q9H3R0 20/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17615785 0.87 KDM4C (0.66) KDM4C
SCHEMBL17615786 0.86 KDM4C (0.54) KDM4C
SCHEMBL17602344 0.85 KDM4C (0.61) KDM4C
SCHEMBL17891432 0.84 KDM4C (0.68) KDM4C
SCHEMBL17615555 0.84 KDM4C (0.59) KDM4C
SCHEMBL17602067 0.80 KDM4C (0.65) KDM4C
SCHEMBL29542236 0.80 KDM4C (0.65) KDM4C
SCHEMBL17891450 0.79 KDM4C (0.61) KDM4C
SCHEMBL17898289 0.79 KDM4C (0.56) KDM4C
SCHEMBL17898286 0.79 KDM4C (0.56) KDM4C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3430008-B1 HISTONE DEMETHYLASE INHIBITORS CELGENE QUANTICEL RES INC (US) 2022-05-18 — — EP disclosed
WO-2017161012-A1 HISTONE DEMETHYLASE INHIBITORS CELGENE QUANTICEL RESEARCH, INC. (US) 2017-09-21 — — WO disclosed
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