Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PHF8 | Q9UPP1 | 13/20 | 0.69 |
| ▸ | KDM4C | Q9H3R0 | 6/20 | 0.68 |
| ▸ | KDM4A | O75164 | 1/20 | 0.61 |
| ▸ | KDM2B | Q8NHM5 | 2/20 | 0.61 |
| ▸ | KDM5A | P29375 | 2/20 | 0.52 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19383318 | 0.86 | PHF8 (0.53) | PHF8KDM4CKDM4AKDM2BKDM5A | |
| SCHEMBL19383320 | 0.83 | PHF8 (0.73) | PHF8KDM4CKDM4AKDM2BKDM5A | |
| SCHEMBL17604527 | 0.83 | KDM4C (0.72) | PHF8KDM4CKDM4AKDM2BKDM5A | |
| SCHEMBL24244156 | 0.82 | PHF8 (0.70) | PHF8KDM4CKDM4AKDM2BKDM5A | |
| SCHEMBL19383405 | 0.82 | PHF8 (0.66) | PHF8KDM4CKDM4AKDM2BKDM5A | |
| SCHEMBL18949682 | 0.82 | PHF8 (0.65) | PHF8KDM4CKDM4AKDM2BKDM5A | |
| SCHEMBL16034307 | 0.81 | KDM4C (1.00) | PHF8KDM4CKDM4AKDM2BKDM5A | |
| SCHEMBL17693134 | 0.81 | PHF8 (0.69) | PHF8KDM4CKDM4AKDM2BKDM5A | |
| SCHEMBL19383018 | 0.80 | KDM2B (0.69) | PHF8KDM4CKDM4AKDM2BKDM5A | |
| SCHEMBL17604673 | 0.79 | PHF8 (0.73) | PHF8KDM4CKDM4AKDM2BKDM5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017161033-A1 | HISTONE DEMETHYLASE INHIBITORS | CELGENE QUANTICEL RESEARCH, INC. (US) | 2017-09-21 | — | — | WO | disclosed |