Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4C | Q9H3R0 | 10/20 | 0.52 |
| ▸ | KDM2B | Q8NHM5 | 3/20 | 0.52 |
| ▸ | PHF8 | Q9UPP1 | 9/20 | 0.51 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.51 |
| ▸ | KDM5A | P29375 | 6/20 | 0.50 |
| ▸ | KDM5B | Q9UGL1 | 6/20 | 0.47 |
| ▸ | KDM4A | O75164 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17604526 | 0.83 | PHF8 (0.48) | KDM4CKDM2BPHF8KDM2AKDM5A | |
| SCHEMBL17604595 | 0.83 | PHF8 (0.48) | KDM4CKDM2BPHF8KDM2AKDM5A | |
| SCHEMBL19383009 | 0.80 | PHF8 (0.58) | KDM4CKDM2BPHF8KDM2AKDM5A | |
| SCHEMBL17604569 | 0.80 | PHF8 (0.58) | KDM4CKDM2BPHF8KDM2AKDM5A | |
| SCHEMBL19383151 | 0.79 | KDM4C (0.55) | KDM4CKDM2BPHF8KDM2AKDM5A | |
| SCHEMBL16033447 | 0.78 | PHF8 (0.58) | KDM4CKDM2BPHF8KDM2AKDM5A | |
| SCHEMBL19383400 | 0.74 | KDM4C (0.60) | KDM4CKDM2BPHF8KDM2AKDM5A | |
| SCHEMBL17604502 | 0.74 | PHF8 (0.59) | KDM4CKDM2BPHF8KDM2AKDM5A | |
| SCHEMBL24244236 | 0.73 | KDM4C (0.65) | KDM4CKDM2BPHF8KDM2AKDM5A | |
| SCHEMBL17604505 | 0.73 | KDM4C (0.79) | KDM4CKDM2BPHF8KDM2AKDM5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3193881-B1 | HISTONE DEMETHYLASE INHIBITORS | CELGENE QUANTICEL RES INC (US) | 2022-02-09 | — | — | EP | disclosed |
| WO-2017161033-A1 | HISTONE DEMETHYLASE INHIBITORS | CELGENE QUANTICEL RESEARCH, INC. (US) | 2017-09-21 | — | — | WO | disclosed |