Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4C | Q9H3R0 | 13/20 | 0.54 |
| ▸ | KDM2B | Q8NHM5 | 7/20 | 0.46 |
| ▸ | NSD2 | O96028 | 6/20 | 0.46 |
| ▸ | KDM5A | P29375 | 7/20 | 0.45 |
| ▸ | KDM5B | Q9UGL1 | 7/20 | 0.45 |
| ▸ | KDM4A | O75164 | 1/20 | 0.45 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16033684 | 0.85 | KDM4C (0.61) | KDM4CKDM2BNSD2KDM5AKDM5B | |
| SCHEMBL16034333 | 0.84 | KDM4C (0.62) | KDM4CKDM2BNSD2KDM5AKDM5B | |
| SCHEMBL16034027 | 0.84 | KDM4C (0.62) | KDM4CKDM2BNSD2KDM5AKDM5B | |
| SCHEMBL16075698 | 0.84 | KDM4C (0.64) | KDM4CKDM2BNSD2KDM5AKDM5B | |
| SCHEMBL16033026 | 0.83 | KDM4C (0.67) | KDM4CKDM2BNSD2KDM5AKDM5B | |
| SCHEMBL16033859 | 0.82 | KDM4C (0.64) | KDM4CKDM2BNSD2KDM5AKDM5B | |
| SCHEMBL16033663 | 0.82 | KDM4C (0.64) | KDM4CKDM2BNSD2KDM5AKDM5B | |
| SCHEMBL16034444 | 0.82 | KDM4C (0.64) | KDM4CKDM2BNSD2KDM5AKDM5B | |
| SCHEMBL16032767 | 0.81 | KDM4C (0.66) | KDM4CKDM2BNSD2KDM5AKDM5B | |
| SCHEMBL16033876 | 0.81 | KDM4C (0.64) | KDM4CKDM2BNSD2KDM5AKDM5B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3436445-B1 | HISTONE DEMETHYLASE INHIBITORS | CELGENE QUANTICEL RES INC (US) | 2023-09-06 | — | — | EP | disclosed |
| EP-3193881-B1 | HISTONE DEMETHYLASE INHIBITORS | CELGENE QUANTICEL RES INC (US) | 2022-02-09 | — | — | EP | disclosed |
| WO-2017161033-A1 | HISTONE DEMETHYLASE INHIBITORS | CELGENE QUANTICEL RESEARCH, INC. (US) | 2017-09-21 | — | — | WO | disclosed |