Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4C | Q9H3R0 | 13/20 | 0.63 |
| ▸ | KDM4A | O75164 | 6/20 | 0.63 |
| ▸ | KDM5B | Q9UGL1 | 12/20 | 0.52 |
| ▸ | KDM2B | Q8NHM5 | 2/20 | 0.52 |
| ▸ | KDM5A | P29375 | 10/20 | 0.50 |
| ▸ | PHF8 | Q9UPP1 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19383301 | 0.90 | KDM5B (0.62) | KDM4CKDM4AKDM5BKDM2BKDM5A | |
| SCHEMBL19383330 | 0.86 | KDM4C (0.64) | KDM4CKDM4AKDM5BKDM2BKDM5A | |
| SCHEMBL20979035 | 0.80 | KDM4C (0.68) | KDM4CKDM4AKDM5BKDM2BKDM5A | |
| SCHEMBL16033641 | 0.78 | KDM4C (1.00) | KDM4CKDM4AKDM5BKDM2BKDM5A | |
| SCHEMBL19383212 | 0.76 | KDM4C (0.60) | KDM4CKDM4AKDM5BKDM5APHF8 | |
| SCHEMBL20979034 | 0.74 | KDM4C (0.68) | KDM4CKDM4AKDM5BKDM2BKDM5A | |
| SCHEMBL18612867 | 0.73 | KDM4C (0.70) | KDM4CKDM4AKDM5BKDM2BKDM5A | |
| SCHEMBL19383324 | 0.72 | KDM5B (0.63) | KDM4CKDM4AKDM5BKDM2BKDM5A | |
| SCHEMBL19383520 | 0.71 | KDM5B (0.52) | KDM4CKDM4AKDM5BKDM2BKDM5A | |
| SCHEMBL19383521 | 0.71 | KDM5B (0.50) | KDM4CKDM4AKDM5BKDM2BKDM5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3436445-B1 | HISTONE DEMETHYLASE INHIBITORS | CELGENE QUANTICEL RES INC (US) | 2023-09-06 | — | — | EP | disclosed |
| WO-2017161033-A1 | HISTONE DEMETHYLASE INHIBITORS | CELGENE QUANTICEL RESEARCH, INC. (US) | 2017-09-21 | — | — | WO | disclosed |