Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4C | Q9H3R0 | 15/20 | 0.71 |
| ▸ | KDM5A | P29375 | 5/20 | 0.71 |
| ▸ | PHF8 | Q9UPP1 | 5/20 | 0.60 |
| ▸ | KDM2B | Q8NHM5 | 7/20 | 0.59 |
| ▸ | KDM5B | Q9UGL1 | 3/20 | 0.49 |
| ▸ | KDM4A | O75164 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19383322 | 0.85 | KDM4C (0.73) | KDM4CKDM5APHF8KDM2BKDM5B | |
| SCHEMBL19383321 | 0.85 | KDM4C (0.74) | KDM4CKDM5APHF8KDM2BKDM5B | |
| SCHEMBL16034821 | 0.83 | KDM4C (1.00) | KDM4CKDM5APHF8KDM2BKDM5B | |
| SCHEMBL19383019 | 0.83 | KDM4C (0.69) | KDM4CKDM5APHF8KDM2BKDM5B | |
| SCHEMBL20978851 | 0.82 | KDM4C (0.73) | KDM4CKDM5APHF8KDM2BKDM5B | |
| SCHEMBL17604600 | 0.79 | KDM4C (0.74) | KDM4CKDM5APHF8KDM2BKDM5B | |
| SCHEMBL16034379 | 0.78 | PHF8 (0.71) | KDM4CKDM5APHF8KDM2BKDM5B | |
| SCHEMBL17604560 | 0.77 | KDM4C (0.70) | KDM4CKDM5APHF8KDM2BKDM5B | |
| SCHEMBL17604553 | 0.77 | KDM4C (0.73) | KDM4CKDM5APHF8KDM2BKDM5B | |
| SCHEMBL16034150 | 0.74 | KDM4C (1.00) | KDM4CKDM5APHF8KDM2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017161033-A1 | HISTONE DEMETHYLASE INHIBITORS | CELGENE QUANTICEL RESEARCH, INC. (US) | 2017-09-21 | — | — | WO | disclosed |