Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4C | Q9H3R0 | 6/20 | 0.67 |
| ▸ | PHF8 | Q9UPP1 | 3/20 | 0.56 |
| ▸ | KDM5B | Q9UGL1 | 7/20 | 0.55 |
| ▸ | KDM2B | Q8NHM5 | 12/20 | 0.50 |
| ▸ | KDM5A | P29375 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19383522 | 0.95 | KDM4C (0.59) | KDM4CPHF8KDM5BKDM2BKDM5A | |
| SCHEMBL26208996 | 0.90 | KDM2B (0.58) | KDM4CPHF8KDM5BKDM2B | |
| SCHEMBL19383338 | 0.90 | KDM4C (0.53) | KDM4CPHF8KDM5BKDM2B | |
| SCHEMBL19383530 | 0.90 | KDM2B (0.58) | KDM4CPHF8KDM5BKDM2B | |
| SCHEMBL19383310 | 0.90 | KDM2B (0.58) | KDM4CPHF8KDM5BKDM2B | |
| SCHEMBL19383529 | 0.88 | KDM2B (0.58) | KDM4CPHF8KDM5BKDM2BKDM5A | |
| SCHEMBL26209034 | 0.88 | KDM4C (0.51) | KDM4CPHF8KDM5BKDM2B | |
| SCHEMBL19383220 | 0.87 | KDM2B (0.60) | KDM4CPHF8KDM5BKDM2B | |
| SCHEMBL19383036 | 0.87 | KDM2B (0.60) | KDM4CPHF8KDM5BKDM2B | |
| SCHEMBL26209075 | 0.87 | KDM4C (0.50) | KDM4CPHF8KDM5BKDM2BKDM5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3436445-B1 | HISTONE DEMETHYLASE INHIBITORS | CELGENE QUANTICEL RES INC (US) | 2023-09-06 | — | — | EP | disclosed |
| WO-2017161033-A1 | HISTONE DEMETHYLASE INHIBITORS | CELGENE QUANTICEL RESEARCH, INC. (US) | 2017-09-21 | — | — | WO | disclosed |