Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM5B | Q9UGL1 | 9/20 | 0.51 |
| ▸ | KDM5A | P29375 | 8/20 | 0.51 |
| ▸ | KDM4C | Q9H3R0 | 11/20 | 0.42 |
| ▸ | KDM4A | O75164 | 6/20 | 0.42 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.41 |
| ▸ | KDM6B | O15054 | 1/20 | 0.39 |
| ▸ | PHF8 | Q9UPP1 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19383527 | 0.93 | KDM5B (0.51) | KDM5BKDM5AKDM4CKDM4AKDM2B | |
| SCHEMBL19383408 | 0.91 | KDM5B (0.52) | KDM5BKDM5AKDM4CKDM4AKDM2B | |
| SCHEMBL19383305 | 0.91 | KDM5B (0.50) | KDM5BKDM5AKDM4CKDM4AKDM2B | |
| SCHEMBL19383523 | 0.90 | KDM5B (0.64) | KDM5BKDM5AKDM4CKDM4AKDM2B | |
| SCHEMBL19383410 | 0.89 | KDM5B (0.52) | KDM5BKDM5AKDM4CKDM4AKDM2B | |
| SCHEMBL19383303 | 0.88 | KDM5B (0.63) | KDM5BKDM5AKDM4CKDM4AKDM2B | |
| SCHEMBL19383302 | 0.86 | KDM5B (0.55) | KDM5BKDM5AKDM4CKDM4AKDM2B | |
| SCHEMBL19383409 | 0.85 | KDM6B (0.53) | KDM5BKDM5AKDM4CKDM4AKDM2B | |
| SCHEMBL19383332 | 0.85 | KDM5B (0.52) | KDM5BKDM5AKDM4CKDM4AKDM2B | |
| SCHEMBL19383518 | 0.83 | PHF8 (0.57) | KDM5BKDM5AKDM4CKDM4AKDM2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3436445-B1 | HISTONE DEMETHYLASE INHIBITORS | CELGENE QUANTICEL RES INC (US) | 2023-09-06 | — | — | EP | disclosed |
| WO-2017161033-A1 | HISTONE DEMETHYLASE INHIBITORS | CELGENE QUANTICEL RESEARCH, INC. (US) | 2017-09-21 | — | — | WO | disclosed |