Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 19/20 | 0.66 |
| ▸ | MAOA | P21397 | 4/20 | 0.63 |
| ▸ | MAOB | P27338 | 6/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20656807 | 0.84 | KDM1A (0.70) | KDM1AMAOAMAOB | |
| SCHEMBL20656806 | 0.84 | KDM1A (0.70) | KDM1AMAOAMAOB | |
| SCHEMBL20656902 | 0.81 | KDM1A (1.00) | KDM1AMAOAMAOB | |
| SCHEMBL19383941 | 0.81 | KDM1A (1.00) | KDM1AMAOAMAOB | |
| SCHEMBL20664107 | 0.80 | KDM1A (0.75) | KDM1AMAOB | |
| SCHEMBL19383931 | 0.80 | KDM1A (1.00) | KDM1AMAOAMAOB | |
| SCHEMBL20664065 | 0.80 | KDM1A (0.64) | KDM1AMAOAMAOB | |
| SCHEMBL19384125 | 0.79 | KDM1A (0.70) | KDM1AMAOB | |
| SCHEMBL20656831 | 0.78 | KDM1A (1.00) | KDM1AMAOAMAOB | |
| SCHEMBL19383937 | 0.78 | KDM1A (1.00) | KDM1AMAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3431471-A1 | FLUORINATED CYCLOPROPYLAMINE COMPOUND, PREPARATION METHOD THEREFOR, PHARMACEUTICAL COMPOSITION THEREOF, AND USERS THEREOF | Shanghai Institute of Materia Medica, Chinese Academy of Sciences (CN) | 2019-01-23 | — | — | EP | disclosed |
| WO-2017157322-A1 | FLUORINATED CYCLOPROPYLAMINE COMPOUND, PREPARATION METHOD THEREFOR, PHARMACEUTICAL COMPOSITION THEREOF, AND USERS THEREOF | 中国科学院上海药物研究所 | 2017-09-21 | — | — | WO | disclosed |