⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20056402 | 1.00 | — | — | |
| SCHEMBL22829682 | 1.00 | — | — | |
| SCHEMBL14120343 | 1.00 | — | — | |
| SCHEMBL16027276 | 0.92 | HK1 (0.51) | — | |
| SCHEMBL16027274 | 0.92 | HK1 (0.51) | — | |
| SCHEMBL15639049 | 0.92 | HK1 (0.47) | — | |
| SCHEMBL15639048 | 0.92 | HK1 (0.47) | — | |
| SCHEMBL16027267 | 0.91 | HK1 (0.48) | — | |
| SCHEMBL16027248 | 0.91 | — | — | |
| SCHEMBL20056314 | 0.91 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3432892-A1 | MANNOSE-DERIVED ANTAGONISTS OF FIMH USEFUL FOR TREATING DISEASE | Fimbrion Therapeutics, Inc. (US) | 2019-01-30 | — | — | EP | disclosed |
| WO-2017165619-A1 | MANNOSE-DERIVED ANTAGONISTS OF FIMH USEFUL FOR TREATING DISEASE | FIMBRION THERAPEUTICS, INC. (US) | 2017-09-28 | — | — | WO | disclosed |