Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 4/20 | 0.78 |
| ▸ | RCOR1 | Q9UKL0 | 3/20 | 0.71 |
| ▸ | LDHB | P07195 | 4/20 | 0.38 |
| ▸ | TERF2IP | Q9NYB0 | 2/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.34 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.34 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.34 |
| ▸ | NPY1R | P25929 | 1/20 | 0.33 |
| ▸ | NPY2R | P49146 | 1/20 | 0.33 |
| ▸ | NPY4R | P50391 | 1/20 | 0.33 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.33 |
| ▸ | TERF2 | Q15554 | 2/20 | 0.33 |
| ▸ | F11 | P03951 | 2/20 | 0.33 |
| ▸ | JAK1 | P23458 | 1/20 | 0.32 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.32 |
| ▸ | STAT1 | P42224 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17860734 | 1.00 | KDM1A (0.78) | KDM1ARCOR1LDHBTERF2IPESR1 | |
| SCHEMBL17882148 | 0.94 | KDM1A (0.81) | KDM1ARCOR1LDHBTERF2IPNPY1R | |
| SCHEMBL19386868 | 0.94 | KDM1A (0.81) | KDM1ARCOR1LDHBTERF2IPNPY1R | |
| SCHEMBL17882235 | 0.94 | KDM1A (0.81) | KDM1ARCOR1LDHBTERF2IPNPY1R | |
| SCHEMBL19386986 | 0.94 | KDM1A (0.81) | KDM1ARCOR1LDHBTERF2IPNPY1R | |
| SCHEMBL19386975 | 0.94 | KDM1A (0.81) | KDM1ARCOR1LDHBTERF2IPNPY1R | |
| SCHEMBL19386984 | 0.91 | KDM1A (0.81) | KDM1ARCOR1LDHBTERF2IP | |
| SCHEMBL19386977 | 0.91 | KDM1A (0.81) | KDM1ARCOR1LDHBTERF2IP | |
| SCHEMBL21476984 | 0.90 | KDM1A (0.88) | KDM1ARCOR1LDHBTERF2IPESR1 | |
| SCHEMBL21504360 | 0.90 | KDM1A (0.88) | KDM1ARCOR1LDHBTERF2IPESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9771394-B2 | Antimicrobial polymyxins for treatment of bacterial infections | MICURX PHARMACEUTICALS, INC. (KY) | 2017-09-26 | — | — | US | disclosed |