Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 3/20 | 0.61 |
| ▸ | RCOR1 | Q9UKL0 | 2/20 | 0.61 |
| ▸ | TERF2IP | Q9NYB0 | 12/20 | 0.38 |
| ▸ | LDHB | P07195 | 2/20 | 0.37 |
| ▸ | TEAD4 | Q15561 | 1/20 | 0.36 |
| ▸ | TEAD3 | Q99594 | 1/20 | 0.36 |
| ▸ | SSTR1 | P30872 | 2/20 | 0.35 |
| ▸ | SSTR2 | P30874 | 2/20 | 0.35 |
| ▸ | SSTR4 | P31391 | 2/20 | 0.35 |
| ▸ | SSTR3 | P32745 | 2/20 | 0.35 |
| ▸ | SSTR5 | P35346 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17882098 | 0.91 | KDM1A (0.75) | KDM1ARCOR1TERF2IPLDHBSSTR1 | |
| SCHEMBL25639947 | 0.87 | KDM1A (0.70) | KDM1ARCOR1TERF2IPTEAD4TEAD3 | |
| SCHEMBL19386844 | 0.82 | KDM1A (0.71) | KDM1ARCOR1TERF2IPLDHBTEAD4 | |
| SCHEMBL19386877 | 0.82 | KDM1A (0.62) | KDM1ARCOR1TERF2IPTEAD4TEAD3 | |
| SCHEMBL19386874 | 0.82 | KDM1A (0.65) | KDM1ARCOR1TERF2IPLDHBTEAD4 | |
| SCHEMBL19386940 | 0.82 | KDM1A (0.65) | KDM1ARCOR1TERF2IPLDHBTEAD4 | |
| SCHEMBL17882097 | 0.81 | KDM1A (0.60) | KDM1ARCOR1TERF2IPLDHBSSTR1 | |
| SCHEMBL21258440 | 0.80 | KDM1A (0.82) | KDM1ARCOR1TERF2IPLDHBTEAD4 | |
| SCHEMBL21335143 | 0.80 | KDM1A (0.81) | KDM1ARCOR1TERF2IPLDHBSSTR1 | |
| SCHEMBL16426327 | 0.80 | KDM1A (0.81) | KDM1ARCOR1TERF2IPLDHBSSTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9771394-B2 | Antimicrobial polymyxins for treatment of bacterial infections | MICURX PHARMACEUTICALS, INC. (KY) | 2017-09-26 | — | — | US | disclosed |