Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 3/20 | 0.55 |
| ▸ | RCOR1 | Q9UKL0 | 2/20 | 0.55 |
| ▸ | TERF2IP | Q9NYB0 | 11/20 | 0.35 |
| ▸ | TERF2 | Q15554 | 2/20 | 0.33 |
| ▸ | DDOST | P39656 | 1/20 | 0.32 |
| ▸ | PRKAR2A | P13861 | 1/20 | 0.32 |
| ▸ | PRKAR2B | P31323 | 1/20 | 0.32 |
| ▸ | LDHB | P07195 | 1/20 | 0.32 |
| ▸ | TEAD4 | Q15561 | 1/20 | 0.32 |
| ▸ | TEAD3 | Q99594 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17882154 | 0.92 | KDM1A (0.66) | KDM1ARCOR1TERF2IPTERF2LDHB | |
| SCHEMBL17860821 | 0.85 | KDM1A (0.77) | KDM1ARCOR1TERF2IPTERF2LDHB | |
| SCHEMBL17882199 | 0.83 | KDM1A (0.55) | KDM1ARCOR1TERF2IPLDHB | |
| SCHEMBL19386931 | 0.82 | KDM1A (0.55) | KDM1ARCOR1TERF2IPLDHB | |
| SCHEMBL25639947 | 0.80 | KDM1A (0.70) | KDM1ARCOR1TERF2IPTEAD4TEAD3 | |
| SCHEMBL17882134 | 0.79 | KDM1A (0.76) | KDM1ARCOR1TERF2IPLDHB | |
| SCHEMBL19386829 | 0.79 | KDM1A (0.76) | KDM1ARCOR1TERF2IPLDHB | |
| SCHEMBL17882037 | 0.79 | KDM1A (0.76) | KDM1ARCOR1TERF2IPTERF2LDHB | |
| SCHEMBL19386940 | 0.78 | KDM1A (0.65) | KDM1ARCOR1TERF2IPTERF2LDHB | |
| SCHEMBL19386874 | 0.78 | KDM1A (0.65) | KDM1ARCOR1TERF2IPTERF2LDHB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9771394-B2 | Antimicrobial polymyxins for treatment of bacterial infections | MICURX PHARMACEUTICALS, INC. (KY) | 2017-09-26 | — | — | US | disclosed |